Now Coenzyme CoQ10 is a strong antioxidant that protects the body from free radicals and helps preserve the body's supply of vitamin E, the major antioxidant for cell membranes and blood cholesterol. Now CoQ10 is also called ubiquinone, a name that signifies its widespread distribution in the human body. Now CoQ10 is used by the body to change food into ATP, the energy source on which the body runs.
CoQ10 supplementation has been researched as a way to improve endurance because of its importance on energy production. Despite this, most research shows that Co-Q10 does not enhance athletic performance. Also other researchers reported no differences in Coenzyme Q10 in muscles or blood from patients with fibromyalgia compared to healthy people.
Because synthesis of sperm requires considerable energy and due to CoQ10's role in energy production, Coenzyme Q10 has been studied in in-fertile men. Preliminary research reportsed that supplementation of Coenzyme Q7, a related molecule, increased sperm counts in infertile men.
Also because healing of periodontal tissue may require increased energy production, researchers have explored the effects of Coenzyme Q10 supplementation in people with periodontal disease. A deficiency in CoQ10 has been linked to periodontal disease. Double blind research shows that people with gum disease who were given CoQ10 achieve better results than those without.
CoQ10 is also involved in how the body uses carbohydrates. Early research suggests that a near relative of this nutrient lowered blood sugar levels in a group of people with diabetes. People with type 2 diabetes have been found to have significantly lower blood levels of CoQ10 as compared with a healthy population.
Almost every cell of the human body contains CoQ10. The mitochondria, the part of cells where energy is produced, contain the most Coenzyme Q10. The liver and heart contain the greatest amounts of CoQ10. CoQ10 has helped some people with congestive heart failure (CHF), an effect noted in an analysis of eight controlled trials and found in some, but not all, double-blind studies. The benfits of CoQ10 may not be seen until after several months. Stopping the use of CoQ10 in people with CHF has resulted in severe relapses and should only be attempted under the supervision of a doctor.
Similar improvements have also been reported in people with cardiomyopathies, a group of diseases affecting the heart muscle. Research (including double-blind studies) in the us of CoQ10 in cardiomyopathies has been consistently positive.
Also, due to its effect on the heart muscle, researchers have studied Coenzyme CoQ10 in people with heart arrhythmias. Early research in this area reported improvement after about one month in people with premature ventricular beats (a form of arrhythmia) that also suffered from diabetes.
Angina patients who took 150 mg per day of CoQ10 report a greater ability to exercise without experiencing chest pain. This has also been confirmed in independently.
CoQ10 appears to increase the heart’s tolerance to a lack of oxygen. Perhaps as a result, preliminary research has shown that problems resulting from heart surgery occurred less frequently in people given CoQ10 compared with the control group.20
Muscle mitochondria lack adequate CoQ10 in people with muscular dystrophy, a problem that could affect muscle function. In a double-blind three-month trial, four of eight people with muscular dystrophy had improvements in heart function and sense of well-being when supplementing CoQ10.21
Mitochondrial function also appears to be impaired in people with Alzheimer’s disease. Due to CoQ10’s effects on mitochondrial functioning, one group of researchers has given CoQ10 (along with iron and vitamin B6) to several people with Alzheimer’s disease and reported the progression of the disease appeared to have been prevented for one and a half, to two years.22
CoQ10 also modulates immunity.23 Perhaps as a result, a few cases have been reported in which women with metastatic breast cancer (cancer that had spread to other tissues) had a regression of their cancer after treatment with a very large amount of CoQ10 (390 mg per day).24
CoQ10 appears to modulate blood pressure by reducing resistance to blood flow.25 Several trials have reported that supplementation with CoQ10 significantly reduced blood pressure in people with hypertension, usually after ten weeks to four or more months of treatment.26